Unsubstituted Phenols
Medchemexpress LLC HY-112734 10mg Medchemexpress, 4'-Methylchrysoeriol CAS:4712-12-3 Purity:>98%
Medchemexpress, HY-112734 10mg 4'-Methylchrysoeriol CAS:4712-12-3 4'-Methylchrysoeriol is a potent inhibitor of Cytochrome P450 enzymes, with an IC50 of 19 nM for human P450 1B1-dependent EROD. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
![Medchemexpress LLC 7-hydroxy-2,3,4,5-tetrahydrobenzofuro[2,3-c]azepin-1-one | 521937-07-5 | 99.1% | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/HY-12239.jpg-250.jpg)
Medchemexpress LLC 7-hydroxy-2,3,4,5-tetrahydrobenzofuro[2,3-c]azepin-1-one | 521937-07-5 | 99.1% | 5 MG
CID755673 is a small-molecule inhibitor of protein kinase D (PKD) with reported IC50 values for PKD1, PKD2, and PKD3. It is supplied as a high-purity solid for research use and is suitable for biochemical, cellular, and in vivo studies.
- Potent PKD inhibition: PKD1 IC50 182 nM, PKD2 IC50 280 nM, PKD3 IC50 227 nM.
- High purity solid suitable for biochemical and cellular assays.
- Soluble in DMSO at 100 mg/mL for in vitro applications.
- Recommended storage: powder at -20°C for long-term stability.
- In vivo dosing examples reported: 1 or 10 mg/kg intraperitoneal in mice.
Medchemexpress LLC Alizarin Red S Indic 10g
Alizarin red S indicator (C I 58005) is a reductively active (quinone-based) anthraquinone dye that forms complexes with metal ions (such as zirconium calcium) or boric acid to label calcium deposition and perform electrochemical sensing functions Alizarin Red S undergoes reversible redox reactions (for electrochemical detection) and irreversible chelation (for bone staining) Alizarin Red S is mainly used in bone metabolism research (labeling mineralized tissue) sugar detection (boric acid-sugar competition system) and metal ion sensing (such as zirconium ion detection) and can be used in osteoporosis and metabolic disease research[1][2][3]
Medchemexpress LLC HY-113093 5mg Medchemexpress, Ethyl glucuronide CAS:17685-04-0 Purity:>98%
Medchemexpress, HY-113093 5mg Ethyl glucuronide CAS:17685-04-0 Ethyl glucuronide is an endogenous metabolite. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 555-66-8 | Medchem Express | Shogaol | 5mg | 446264383 | HY-14616 | MFCD01736094 | 276.376 | C17H24O3
Medchem Express | Shogaol | 5mg | 446264383 | HY-14616 | 555-66-8 | MFCD01736094 | 276.376 | C17H24O3
Medchemexpress LLC 2-hydroxy-3-nitro-5-(phenylmethyl)-benzaldehyde | 328565-16-8 | 99.9% | 257.24 g·mol-1 | C14H11NO4 | 25MG
Col003 is a small-molecule inhibitor of heat-shock protein 47 (Hsp47) that competitively binds the collagen-binding site and inhibits Hsp47 with an IC50 of 1.8 μM. It is supplied as a high-purity solid suitable for biochemical and cell-based studies investigating collagen-Hsp47 interactions, target validation, and assay development.
- Selective inhibitor of Hsp47.
- Reported IC50 of 1.8 μM.
- Competitively binds the collagen-binding site on Hsp47.
- High purity (99.87%) and characterized by analytical data.
- Available in multiple small-mass pack sizes for research use.
- Molecular weight 257.24 g·mol-1 and formula C14H11NO4.
Medchemexpress LLC Licochalcone B | 58749-23-8 | 286.28 | 1 MG
Licochalcone B is an extract from the root of *Glycyrrhiza uralensis*. It inhibits amyloid β (42) self-aggregation (IC50=2.16 μM) and disaggregates pre-formed Aβ42 fibrils. It also reduces metal-induced Aβ42 aggregation by chelating metal ions. Licochalcone B inhibits the phosphorylation of NF-κB p65 in the LPS signaling pathway, inhibits the growth and induces apoptosis of NSCLC cells, and specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction.
- Inhibits amyloid β (42) self-aggregation and disaggregates pre-formed Aβ42 fibrils.
- Reduces metal-induced Aβ42 aggregation through chelating metal ions.
- Inhibits phosphorylation of NF-κB p65 in the LPS signaling pathway.
- Inhibits growth and induces apoptosis of NSCLC cells.
- Specifically inhibits the NLRP3 inflammasome by disrupting NEK7‐NLRP3 interaction.
- Purity: 99.91%.
Medchemexpress LLC Diosmetin 7-o-beta-d-glucuronide | 35110-20-4 | 10 MG
Diosmetin 7-o-beta-d-glucuronide is an antioxidant constituent found in the fruits of Luffa cylindrical.
- Product type: Natural products
- Targets others
Medchemexpress LLC HY-16950 50mg , 4-Hydroxytamoxifen (Z)-4-Hydroxytamoxifen;trans-4-Hydroxytamoxifen CAS:68047-06-3 Purity:98%
Medchemexpress, HY-16950 50mg 4-Hydroxytamoxifen (Z)-4-Hydroxytamoxifen;trans-4-Hydroxytamoxifen CAS:68047-06-3 Formula:C26H29NO2 IC50: 3.3 nM (Oestrogen receptor) CRISPR/Cas9 Purity:98% 4-Hydroxytamoxifen, an active metabolite of tamoxifen, is a selective estrogen receptor antagonist, with an IC 50 of 3.3 nM for the [ 3 H]oestradiol binding to oestrogen receptor, widely used to treat breast cancer; 4-Hydroxytamoxifen also increases CRISPR/Cas9 -mediated editing frequency. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Sigma Aldrich Fine Chemicals Biosciences Phenol BioUltra, for molecular biology, >=99.5% (GC) | 108-95-2 | MFCD00002143 | 100G
Phenol BioUltra, for molecular biology, >=99.5% (GC) | Purity: >=99.5% (GC) | Mol Wt: 94.11 | 108-95-2 | MFCD00002143 | 100G
Medchemexpress LLC Protac Bcl-xL ligand-1 | 3029365-95-2 | 99.1% | C32H29IN4O4S2 | 10MG
PROTAC Bcl-xL ligand-1 is a small-molecule ligand for the anti-apoptotic protein Bcl-xL, intended as a building block for proteolysis-targeting chimera (PROTAC) synthesis and related biochemical research. The compound is characterized by CAS 3029365-95-2, molecular formula C32H29IN4O4S2, molecular weight 724.63, and a manufacturer-reported purity of 99.06%. Safety data and handling information are provided in the product SDS.
- High reported purity (99.06%).
- Characterized by CAS number and molecular identifiers.
- Suitable for use in PROTAC synthesis and ligand development.
- Available in multiple small-molecule quantities for research use.
- Safety data sheet and handling guidance available.
![Medchemexpress LLC N-[5-amino-1,2,3,4-tetrahydro-1-[4-(trifluoromethyl)phenyl]-3-quinolinyl]-2-propenamide | 2766575-48-6 | MFCD22417285 | 99.8% | 361.36 | C19H18F3N3O | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000285876.png-250.jpg)
Medchemexpress LLC N-[5-amino-1,2,3,4-tetrahydro-1-[4-(trifluoromethyl)phenyl]-3-quinolinyl]-2-propenamide | 2766575-48-6 | MFCD22417285 | 99.8% | 361.36 | C19H18F3N3O | 10 MG
SWTX-143 is a covalent, irreversible inhibitor of the YAP/TAZ-TEAD transcriptional complex developed for research. It binds the palmitoylation pocket of TEAD isoforms and suppresses YAP/TAZ-TEAD transcriptional activity, and has demonstrated oral activity in preclinical studies. The compound is supplied as a high-purity solid intended for biochemical and cell-based research applications.
- Covalent, irreversible inhibitor of YAP/TAZ-TEAD.
- Binds the palmitoylation pocket of TEAD isoforms.
- Inhibits YAP/TAZ-TEAD transcriptional activity.
- Demonstrated oral activity in preclinical studies.
- High reported purity (about 99.8%).
- Supplied as a white to off-white solid.
- Available in milligram-scale packages for laboratory research.
- Suitable for biochemical and cell-based assays.
Medchemexpress LLC Ko 143 | 461054-93-3 | 100.0% | 469.57 | 25MG
Ko 143 is a potent and selective ATP-binding cassette subfamily G member 2 (ABCG2/BCRP) inhibitor. This compound demonstrates over 200-fold selectivity compared to P-gp and MRP-1 transporters.
- Potent and selective ABCG2/BCRP inhibitor.
- Shows over 200-fold selectivity compared to P-gp and MRP-1 transporters.
- Has an EC90 of 26 nM for BCRP.
![eMolecules 225937-10-0 | (+)-Catechin hydrate | Combi-Blocks308.286 | C15H16O7 | 97.000 | O.O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1ccc(O)c(O)c1 | 1g | 495747478](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183916.JPG-250.jpg)
eMolecules 225937-10-0 | (+)-Catechin hydrate | Combi-Blocks308.286 | C15H16O7 | 97.000 | O.O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1ccc(O)c(O)c1 | 1g | 495747478
(+)-Catechin hydrate | Combi-Blocks | 225937-10-0308.286 | C15H16O7 | 97.000 | O.O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1ccc(O)c(O)c1 | 1g | 495747478
ILEX LIFE SCIENCES LLC TRYPSINEDTA P10-020500 6X500ML
PAN-Biotech Trypsin 0.25% / EDTA 0.02% in DPBS, w/o: Ca and Mg (6 x 500 ml). DESCRIPTION: PAN-Biotech Trypsin 0.25% / EDTA 0.02% in PBS, w/o: Ca and Mg is a porcine pancreas-derived enzyme plus EDTA in a PBS solution. Trypsin-EDTA solution is commonly used for the dissociation of anchorage-dependent (adherent) mammalian cells and tissues from culture surfaces. The concentration of trypsin necessary to dislodge cells from their substrate is dependent on the cell type and the age of the culture. Ethylenediaminetetraacetic acid (EDTA), a chelating agent, is often added to trypsin solutions to enhance enzymatic activity by neutralizing calcium and magnesium ions that enhance cell-to-cell adhesion and obscure the peptide bonds on which trypsin acts. LIQUID/POWDER: Liquid. PHENOL RED: Without Phenol Red. Ca/Mg CONTENT: Without Ca and Mg. TRYPSIN: 0.25% Trypsin. EDTA: 0.02% EDTA. STERILE: Yes. STORAGE TEMP.: -20°C. MANUFACTURER: PAN-Biotech GmbH (Germany).